Updated

Researchers have identified an enzyme called UBE2N that appears to act as a natural defense mechanism against the worsening of fatty liver disease, a condition affecting an estimated 100 million Americans. The enzyme helps liver cells clear damaged mitochondria and break down fat, potentially slowing progression toward the more dangerous MASH condition. The finding could open new therapeutic avenues aimed at boosting UBE2N activity to prevent inflammation, scarring, and further liver damage in at-risk patients.