Updated

Actor Christina Applegate revealed that she had been misdiagnosed with multiple sclerosis, triggering discussion about the frequency of MS misdiagnosis across the medical field, reported October 22, 2026. The disclosure raised important questions about how often people are told they have the condition when they do not. Dr. Michael Kornberg of Johns Hopkins University discussed with PBS NewsHour why MS can be so difficult to diagnose, highlighting systemic challenges in detecting the neurological disease accurately.